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Dementia and depression have been associated with this deficiency as well, possibly from the under-production of methionine because of the inability to convert homocysteine into this product

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doi:10.1016/j.scitotenv.2015.01.098 Subedi B, Lee S, Moon H-B, Kannan K (2013) Psychoactive pharmaceuticals in sludge and their emission from wastewater treatment facilities in Korea

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Glutamate : It also influences the AMPA receptors in the glutamatergic system, which play a critical role in long-term potentiation (LTP) and synaptic plasticity