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Recently published subgroup analyses have explored the role of background use of metformin as a potential effect modifier of cardiovascular benefit

This article examines how GLP-1 therapies work, the clinical evidence supporting their use, current prescribing criteria within NHS pathways, and essential monitoring considerations for patients with concurrent metabolic and liver conditions

SGLT-2 inhibitors have a well-established association with genital mycotic infections, while the evidence for increased UTI risk is mixed

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While yet to be authorized for human use by regulatory authorities such as the FDA, retatrutide is currently in phase 3 clinical trials under Eli Lillys TRIUMPH development program