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doi: 10.1007/s12026-022-09296-7 118 JacksonSWJacobsHMArkatkarTDamEMScharpingNEKolhatkarNSet al

Synergistic effects: SAMe may also exhibit synergistic effects when combined with other treatments, such as painkillers or antidepressants, which can enhance its therapeutic potential in FM management [69, 70]

Standard initial treatment for patients: Without neurological involvement: 1000 g intramuscularly three times a week for two weeks

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