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Discontinuation rates in randomized CV outcome trials As presented in Table 4, some patients randomized to GLP-1 RA treatment discontinued the assigned medication

Rajamanickam, G

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It should be noted that hyperuricemia in both men and women is a significant contributor to the development of non-alcoholic fatty liver disease (NAFLD), diabetes, the metabolic syndrome, and obesity

This constellation of symptoms can occur in type 2 diabetes but suggest insulin deficiency and raise the possibility of autoimmune (type 1) or pancreatogenic diabetes in which insulin would be the preferred therapy