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The decreased whole lung GSH levels in these animals were further accompanied by a Th2-mediated inflammatory response evidenced by increased airway eosinophil influx

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Since immune cell trafficking into the CNS is tightly regulated by the blood brain barrier which selectively only allows entry of immune cell subsets required for immune surveillance (80), it remains unknown if CAR-T would efficiently reach senescent cells in the brain parenchyma

doi: 10.1038/s41598-019-56631-4 [DOI] [PMC free article] [PubMed] [Google Scholar] Gao J

J Biomed Sci 24(1):78

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