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3.1.1 HIF-regulated erythropoietin The EPAS1 gene, which encodes HIF-2, has been identified as the predominant isoform involved in high-altitude adaptation on the basis of recent genome-wide studies (20)

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Persistently high levels are more commonly linked to supplements or medical conditions

These relationships may inform clinical decision-making in situations where treatment switching is required as a result of availability, cost, or tolerability considerations

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4) CD163 and PC are dysregulated genes validated to associate with lipid peroxidation