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This dual action is one reason why tirzepatide might provide additional benefits when used alongside semaglutide

Ghrelin and growth hormone (GH) secretagogues potentiate GH-releasing hormone (GHRH)-induced cyclic adenosine 3,5-monophosphate production in cells expressing transfected GHRH and GH secretagogue receptors

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Week 17 onward (2.4 mg, 48 units at 5 mg/mL): The maintenance dose