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Description

Using biochemical and genotype data from a previously published PCOS genome-wide association study and GEO database, SVM, RF, unsupervised hierarchical cluster analysis, and Gaussian mixed model (GMM) were performed to investigate the hypothesis that there were biologically reproducible phenotypic relevant subtypes of PCOS with subtype-specific genetic associations, regarding reproductive and metabolic PCOS subtypes, as well as hyperandrogenemia and non-hyperandrogenemia PCOS subtypes [29, 107]

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