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As a dual amylin and calcitonin receptor agonist (DACRA), Cagrilintide engages both amylin and calcitonin receptors, amplifying its therapeutic potential

66 The peptides ability to maintain blood flow (by promoting new blood vessels or bypassing clots) is thought to play a role in these protective effects

PCO is the most common complication and when it occurs, it can lead to secondary vision loss or blindness in 3050% of adults and in 100% of children (7)

Jeong WY, Kwon M, Choi HE, Kim KS

Trickett, S

Overall, the core molecular machinery of ferroptosis is regulated by various cellular signalling pathways and genes but is primarily mediated through two main pathways, namely, extrinsic or transporter-dependent pathways (e.g., reduced cysteine or glutamine uptake and increased iron uptake) and intrinsic or enzyme-regulated pathways (e.g., inhibition of glutathione (GSH) peroxidase 4 (GPX4) antioxidant system) (Fig