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Furthermore, epigenetic age acceleration (EAA), an epigenetic biomarker of aging, has been linked to indoor air pollution from coal combustion and associated pulmonary arterial hypertension, particularly 5-methylcytosine, which correlates with the mortality biomarker Grim Age EAA [158]

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Regardless of supplementation, long-term results still depend primarily on: Consistent exercise Balanced nutrition Sleep quality Hydration Recovery habits When selecting supplements, prioritising transparent formulations and responsible usage practices may help support safer and more informed fitness decisions

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Nature 607 , 249255 (2022)