clarified the transport route of L-penetratin-aided nose-to-brain delivery of insulin and exendin-4 (Kamei et al., 2021)
Episode #1 Some days I eat more, and some days I eat less
Key Takeaways BPC-157 is a synthetic peptide, made up of fifteen amino acids This peptide is studied in the laboratory and medical literature Researchers investigate it for its stability, cellular signaling activity, and the part it plays in experimental tissue and gastrointestinal biology The majority of published evidence comes from in vitro and animal studies BPC-157 isnt FDA-approved as a therapeutic drug, although its regulatory status continues to evolve as additional evidence is evaluated
doi: 10.1083/jcb.201701136 56 KanCFSinghABStafforiniDMAzharSLiuJ
Third, delivery methods are improving
Nuclear factor erythroid 2-related factor 2 (Nrf2), a master transcription factor that maintains intracellular redox homeostasis, plays a key role in cellular protection mechanisms by sensing oxidative stress in normal physiological environments (Helou et al