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GHK-CU - Research Grade Peptide

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Brister D, Rose S, Delhey L, Tippett M, Jin Y, Gu H, Frye R

Agents Linaclotide [5] Peptide agonist of guanylate cyclase-C Increases intestinal secretion of bicarbonate, chloride, and fluid, which improves fecal transit Lubiprostone [5] Prostaglandin derivative that activates chloride channels on the apical surfaces of enterocytes Increases intestinal fluid secretion and improves fecal transit Plecanatide [22] A guanylate cyclase-C agonist Increases intestinal secretion of bicarbonate, chloride, and fluid, which improves fecal transit Adverse effects Special patient groups Constipation in infants, children, and adolescents is detailed separately

Ethics declarations Competing interests All authors are current or former employees of 23andMe