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It primarily affects infants and is most commonly found in the head and neck region, with 70% of cases occurring in the maxilla, 11% in the skull, and 6% in the mandible

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In addition to its anti-apoptotic effect on mitochondria, Bcl-2 can inhibit pathways independent of Apaf-1 and caspase 9 and caspase-7-dependent pathways by indirect control of apoptosome activation