thus, specific amino acid deprivation by drugs (e.g., apilimod, DQ661, and bafilomycin A1), which shut down nutrient scavenging pathways (e.g., suppressing lysosomal fusion, acidification, and nutrient export from lysosome), have aroused great interest (Gayle et al., 2017
Understanding the role of the kynurenine pathway in human breast cancer immunobiology
The emerging understanding of MOTS-c in diabetes may provide insight into the development of new therapies for diabetes and other age or senescence-related diseases
Amino acid sensing by mTORC1: intracellular transporters mark the spot
Theyre more effective as a pair than either one alone
An RCT combining NAC with pirfenidone found no additional lung function benefit but increased photosensitivity (142)