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Human atopic dermatitis biopsy studies showed effects similar to or better than comparative steroids

This occurs through an indirect mechanism by reducing the synthesis and secretion of antiadipogenic cytokines by malignant epithelial cells and fibroblasts

UNESCO, United Nations Educational, Scientific and Cultural Organization

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6C, E, F), and 22 genes that were downregulated in control cells and significantly upregulated by NRF2 in the presence of Cyss (3 genes: STXBP6 , INHBB , and TRIM16L ), in the absence of Cyss (14 genes: SLC5A3 , ANGPT1 , GCLM , PPARA , IGF2BP3 , TGFBR3 , POLR3G , GPR157 , CHIC1 , SLC18A2 , FSD1L , SRXN1 , SLC2A13, and RGS17 ) or in both conditions (5 genes: TXNRD1 , RP11-443P15.2 , AKR1B10 , OSGIN1 , and TNIP3 ) compared to control cells treated in the same way (Fig

Hayashi M, Mishima K, Fukumizu M, Takahashi H, Ishikawa Y, Hamada I, et al