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In connective tissue and skeletal muscle research settings, investigators typically follow markers such as collagen expression, satellite cell activation, growth-factor receptor dynamics, angiogenic mediators, and inflammatory signaling nodes

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DeFoor, W

This heightens susceptibility to the toxic effects of iron overload, disrupting intestinal mucosal homeostasis and triggering local inflammation and cell death, ultimately precipitating the onset of gut-associated diseases ( Iron overload-related diseases rank among the most prevalent genetic disorders in humans, characterized pathologically by systemic iron accumulation resulting from excessive dietary iron absorption and iron-induced oxidative stress responses ( 3 Ferroptosis and inflammatory bowel disease The imbalance in ferroptosis regulation plays a key role in the pathogenesis of various diseases

Fayed et al., 2023