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Determinants of the impaired secretion of glucagon-like peptide-1 in type 2 diabetic patients

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The polymorphism in GSTM1 and GSTT1 genes, leads to complete lack of activity of their corresponding enzymes and is responsible for poor elimination of carcinogenic substances which are potential sources of reactive oxygen species (Rebbeck, 1997

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I carefully monitored my caloric intake to ensure I wasnt losing weight too rapidly