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Strategies for repositioning and repurposing drugs using existing drugs for new therapeutic applications offer promising approaches to treating neurological and psychiatric diseases associated with insulin resistance and neurodegeneration

The influence of GLP-1 on glucose-stimulated insulin secretion: effects on beta-cell sensitivity in type 2 and nondiabetic subjects

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Results The search strategy identified 833 hits, of which 42 studies were included in the final review

Of the preclinical studies examined, 22 showed a reduction in amyloid-beta plaques, and 19 showed a reduction in tau tangles

They only stimulate insulin release when blood sugar is elevated