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Glutathione is a key player in the livers "Phase II" detoxification pathway

Shin J, Song MH, Oh JW, Keum YS, Saini RK

In: MarcoI, editor

When antioxidant levels are insufficient to keep the free radicals in check, the free radicals start to damage proteins, lipids, and DNA, triggering various illnesses and health conditions, including the following: Lung diseases: Oxidative stress, such as that caused by smoking tobacco products, is related to a number of lung diseases, including asthma, chronic obstructive pulmonary disease (COPD), acute lung injury (ALI), pulmonary fibrosis, and lung cancer

The FAK-paxillin pathway is central to cell adhesion, migration, and proliferation

Research in dogs with liver disease has shown altered glutathione concentrations in liver tissue, underscoring that antioxidant status can shift with hepatic conditions (Center SA, 2002)