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In ATTAIN-MAINTAIN, participants were randomized to a 12 mg dose of once-daily, oral orforglipron (or matching placebo) which was increased every 4 weeks until the randomized maintenance dose of 36 mg or MTD (24 mg or 36 mg) was reached

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adults who qualified for semaglutide, 35 million would administer it for diabetes management, 129.2 million for weight loss, and 8.9 million for secondary prevention of cardiovascular disease

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