These mechanisms include enhanced DNA repair capabilities, increased efflux of the drug, and profound alterations in cellular metabolism promoting tumor survival ( The reprogramming of cellular metabolism was proposed as a common type of tumor resistance decades ago, but the complexities and uniqueness of certain alterations in a tissue specific manner have only been described in the last decade
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This unique characteristic has made BPC-157 a compelling tool for researchers exploring novel mechanisms of tissue repair, cytoprotection, and homeostatic regulation
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