Metabolism Open, 22, 100291
Older work characterized DSIP as a sleep-modulating peptide rather than a sedative, with a U-shaped activity curve where small doses or short infusions produced the strongest effect
However, neither BAL fluid nor intracellular GSH, GSSG, and GSH:GSSG correlated with BAL eosinophils or any other inflammatory cell, suggesting eosinophilia plays a lesser role in contributing to higher extracellular/BAL fluid GSSG than epithelial cells do (Supplemental Tables 3 and 4)
And when I read these stories, I thought: I know this feeling
The standard starting dose is 0.5mg once weekly, with increases every four weeks following a structured schedule
The short version is that these are not competing drugs