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GLP-1 receptor agonist medications (like Semaglutide and Tirzepatide) mimic this hormone , amplifying its effects: These combined effects create a metabolic resetallowing your body to shift from fat storage mode to fat-burning mode, while reducing the emotional and biological triggers that make weight loss hard to sustain

The review also outlines actionable directions for future work, including model explainability, support for low-resource languages, and closer collaboration with regulatory authorities to enable real-world deployment

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doi: 10.1016/j.ecoenv.2020.111887 22

Moreover, energy and substrate metabolism might provide new interventional targets for the prevention or treatment of hypertension