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doi: 10.1007/s11892-015-0657-7 39 RussoLMarsellaCNardoGMassignanTAlessioMPiermariniEet al

Excessive levels of ROS potentiate lipid peroxidation events, which inhibit small molecules of aldehydes, such as acrolein, malondialdehyde, and 4-hydroxynonenal (4-HNE)

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Inhibition of NAD+ also resulted in increased acetylation of SOD2 , PGC-1 , GCN5 , and p65

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