Most patients experienced gastrointestinal side effects, particularly at higher doses, though lower monthly doses showed fewer issues
Oral intake of 2,400 mg/day for two weeks was also found to be safe in a pilot study that included participants with multiple sclerosis (95)
Accordingly, incretin-based therapies, such as DPP-4 inhibitors and GLP-1 receptor agonists (GLP-1 RAs) that are resistant to degradation by DPP-4, have been introduced in the market within the past decade to overcome and extend the short half-life of the incretin effect
Caution: Peptide therapies must always be done under qualified medical supervision and guidance
Consult with a qualified healthcare provider before beginning any peptide protocol
The lack of reimbursement in some healthcare systems represents an additional structural barrier to equitable access