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When metformin alone is insufficient, NICE recommends considering the addition of one of several medication classes: SGLT2 inhibitors (such as dapagliflozin, empagliflozin, or canagliflozin) work by increasing glucose excretion through the kidneys

Incorporating a variety of whole, nutrient-dense foods while limiting calorie intake and avoiding processed foods can help achieve lasting results

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Among the top 12, the biggest climbers were AstraZeneca, Eli Lilly, and Novo Nordisk

Its also important to be aware of possible side effects, such as ongoing nausea or serious injection-site reactions

Vani GT, Mukesh N, Siva Prasad B et al (2010) Role of glutathione S-transferase Mu-1 (GSTM1) polymorphism in oligospermic infertile males