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If someone has certain genetic mutations, these conversion processes may not function efficiently, making it difficult for cells to absorb and use vitamin B12 effectively

Vitamin B12 is responsible for making red blood cells, white blood cells, and platelets

For instance, as red blood cell production accelerates (typically beginning 3-5 days after treatment starts), iron stores may be utilised more rapidly

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Aging reduces NAD+ synthesis pathways while increasing consumption by enzymes like CD38 and PARPs, activated by inflammation and damage.[13][15] CD38, an immune-related enzyme, ramps up with age, breaking down NAD+ precursors

2025 [cited 3rd June 2025] CDSCO [Internet]