fda glp-1 safety alert october 2025 New project announcement: HHS‑OIG is taking a closer look at FDA's oversight of compounded GLP‑1 drugs. Although shortages ended in 2025, some facilities may still be producing these drugs at scale. Our How safe are GLP-1s? -

2025;328(3):H450H461

Understanding whether these medications directly cause tiredness, the contributing factors, and effective management strategies is essential for patients and healthcare providers

Animal studies serve an important role in identifying potential concerns that warrant human investigation

Ozempic (semaglutide injection) Summary of Product Characteristics

miRNA-mediated and epigenetic regulatory mechanisms GLP-1RAs participate in the epigenetic regulation of the processes of tumorigenesis and cancer progression by modulating gene expression and changes in DNA methylation

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