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393 These encouraging results have prompted two clinical trials, NCT03840005 (phase II) and NCT02967250 (phase I), which investigate the application of UDCA in PD patients

thus, partially explaining the lack of effectiveness in altering the inflammatory equilibrium which evidently must go through delayed processes of signalling pathways and transcription

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This allows for higher bioavailability than oral supplements, which are often broken down in the gut before they can be effectively absorbed

Wood TB, Spivey WTN, Easterfield TH