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Hepatic Antioxidant System The pivotal involvement of the liver in cleansing blood from the gut (considered to be the richest source of oxidants and toxins in the body), it's central role in intermediary metabolism and detoxification processes, its large active Kupffer cell (macrophage) population, imposes high risk for exposure to injurious substances, infectious agents, toxic adducts, and oxidizing substrates

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It may also be worthwhile to reanalyze gene expression datasets obtained from CaP models in which coregulator function is altered and apply ceRNA analyses to gain insights into cooperating transcript networks

Until then, we lack long-term safety data, and we dont know whether microdosing GLP-1s is effective or safe