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These are not small improvements

and avoiding ultraprocessed and restaurant foods high in refined starch, sugar, salt and additives

doi:10.1351/pac199365061189

Options for managing tolerance include a brief dose reduction for 4 to 8 weeks ("drug holiday" at a lower dose, not complete cessation), lifestyle optimization to maximize the medication effect, evaluation for other contributing factors (thyroid function, cortisol, sleep quality, medication interactions), and consideration of adding a complementary compound to address specific aspects of the plateau

Rybelsus is the first oral semaglutide approved by the FDA to improve blood sugar control in adults with type 2 diabetes

Maternal BMI has great potential to affect pregnancy outcomes and would likely benefit from further research