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p = 0.012)

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The analysis was performed using a statistical software program (GraphPad, San Diego, CA, USA)

The hyperkalemia associated with Gordon syndrome is due to the fact that WNK1 and WNK4 normally activate the renal outer medullary K + channel (ROMK, encoded by the KCNJ1 gene) present in the apical membranes of late distal convoluted tubule (DCT2) cells and connecting tubule cells

Die Aufreinigung von GST-Fusionsproteinen mittels Glutathion(GSH)-Agarosebeads ist umfassend dokumentiert und an eine Vielzahl von Mastbe, Sulenformate und spezifische Anwendungen anpassbar