Cell 177 , 722736.e722 (2019)
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It stimulates collagen production in dermal fibroblasts by up to 70% at optimal concentrations around 1 nanomolar
Consequently, impaired ketogenesis and production of BHB in COVID-19 ARDS may be at the root of the metabolic dysregulation and defective effector function of T cells, and may predispose patients to pulmonary pathology, including fibrosis
[DOI] [PMC free article] [PubMed] [Google Scholar] 260.Vartivarian SE, Anaissie EJ, Cowart RE, Sprigg HA, Tingler MJ, Jacobson ES