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What it does in the MicroInfuser context: dermal hydration (low-MW), volumetric plumping in upper dermis (mid-MW), barrier-protective film in the post-procedure window (high-MW), and CD44 receptor engagement on fibroblasts

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PMID: 5 MoroKYamadaTTanabeMTakeuchiTIkawaTKawamotoHet al

Kidney dysfunction or recurrent volume depletion: severe vomiting or diarrhea can worsen renal function

This model uncouples DNA repair from gene expression, demonstrating this is likely a direct effect on chromatin, not changes in transcription of DNA repair factors