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These medications are synthetic analogs or mimetics of human GLP-1 that resist degradation by the enzyme dipeptidyl peptidase-4 (DPP-4), allowing for prolonged therapeutic action

Donc, de faon indirecte, la mthylcobalamine joue aussi un rle dans la synthse de la thymidine (substance importante pour le mtabolisme des nuclotides)

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In the first two studies, changes in redox and methylation metabolism were reported but because the studies were open-label the changes in these biomarkers were not compared to a placebo group