Introduction of exogenous antioxidants combats ferroptosis As IR strongly induces ROS generation and inhibits GPX4 antioxidant activity, introducing exogenous antioxidants is an intuitive anti-ferroptosis strategy
Stettner, T
[DOI] [PubMed] [Google Scholar] 96.de Zeeuw D., Akizawa T., Audhya P., Bakris G.L., Chin M., Christ-Schmidt H., Goldsberry A., Houser M., Krauth M., Lambers Heerspink H.J., et al
A DNMT3A mutation common in AML exhibits dominant-negative effects in murine ES cells
[46] used yes or no questions, and the response rate to particular questions could be taken, at least in part, as a surrogate indicator of recall
Cytoprotective effects against viruses like SARS-CoV-2 could be enhanced by sulforaphane, an isothiocyanate abundant in cruciferous vegetables, since sulforaphane has been found to be a powerful activator of the Nrf2 pathway by increasing Nrf2-regulated cellular antioxidant response such as induction of NAD(P)H: quinone oxidoreductase 1, glutamate-cysteine ligase (-glutamyl cysteine synthetase) and glutathione (Theodore et al., 2008