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Despite the common reliance on self-reported measures, there is low concordance between subjective assessments and physiological sleep measurements 7,8 , especially among individuals with higher depression severity 9

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While doctors may sometimes prescribe Ozempic or Mounjaro "off-label" for weight loss, insurance coverage is typically tied to the FDA-approved indication

doi: 10.1074/jbc.272.52.32810 11 RouilleYWestermarkGMartinSKSteinerDF

A meta-analysis found GLP1RAs exhibit antidepressant effects, particularly in T2D, with liraglutide showing notable efficacy over exenatide, though subgroup differences were not significant 62