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The authors realized that glutamate, glycine and serine were consistently impacted by metabolic disease and developed the GSG-Index, Glutamate/ (Serine+Glycine)

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It allows for the analysis of coordinated modulation of nitric oxide signaling, cytokine production, extracellular matrix remodeling, and pathways related to progenitor cells

[DOI] [PMC free article] [PubMed] [Google Scholar] 46.Horwood NJ, Page TH, McDaid JP, Palmer CD, Campbell J, Mahon T, Brennan FM, Webster D, and Foxwell BM 2006

Wrinkle depth has reduced significantly