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OXCT1 functions as a succinyltransferase, contributing to hepatocellular carcinoma via succinylating LACTB

In vivo tests revealed that MIC1 significantly enhanced the Bax/Bcl2 ratio in tumor tissues and considerably prevented the formation of mouse tumors

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(2016) demonstrated in mouse models of middle cerebral artery occlusion that large ischemic strokes induce gut dysbiosis characterized by reduced diversity and Bacteroidetes overgrowth, leading to intestinal barrier dysfunction