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. In addition to weight loss, participants on orforglipron saw improvements in key cardiovascular risk markers, including non-HDL cholesterol, triglycerides, systolic blood pressure, and high-sensitivity C-reactive protein

Phentermine : A stimulant that suppresses appetite, typically used short-term in combination with lifestyle changes

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While these mechanisms support weight loss and metabolic improvements, they function differently from metabolic stimulants that directly increase energy expenditure or thermogenesis

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