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Multiple phase 2 and 3 trials support the use of incretin drugs in chronic kidney disease (CKD) [14], osteoarthritis [15], obstructive sleep apnea (OSA) [16] and even in early Parkinsons disease [17], demonstrating the pleiotropic benefits of these agents in preventing chronic disease progression (Fig

Retatrutide has no UK marketing authorisation

Contact your GP if you experience severe or worsening joint pain, joint swelling or redness, sudden intense pain in a single joint, persistent pain lasting more than two weeks, or joint stiffness lasting over 30 minutes after waking

10.1007/s00213-020-05634-5 168 ZimmermanA

The use of semaglutide in patients with diabetes was associated with a significantly increased risk for nonarteritic anterior ischemic optic neuropathy (NAION) compared with those taking drugs for diabetes that belong to other classes of medication

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