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This warning is not based on human epidemiology alone but largely originates from rodent toxicology studies , where GLP-1 receptor activation led to: Increased calcitonin secretion C-cell hyperplasia C-cell adenomas and carcinomas in rats/mice These findings have been consistently observed across multiple GLP-1 receptor agonists
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Ozempic is approved for treating type 2 diabetes, with weight loss as a secondary benefit
218(2): 41727 Kuroda N, Ohyama Y, Nakashima K, et al
"Dose optimization strategies for minimizing GLP3 side effects in research settings." International Peptide Review , 18(2), 123-139
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