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J Biol Chem 2008;283:22700-8

Not yet, particularly since GLP-1s are not approved to treat anything beyond diabetes, obesity, and obesity-related health issues

For the majority of patients in clinical trials, tirzepatide resulted in greater weight loss and better blood sugar control due to its dual GIP and GLP 1 action

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The Phase 2 readout established the dose-response signal that the Phase 3 program later confirmed at scale

In fairness, there are plenty of folks who have no interest in savoring their morning beverage and instead need to put the liquid inside them as fast as possible so they can adult that day