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The findings, published in The New England Journal of Medicine and presented at the American Heart Association Scientific Sessions 2024, highlight tirzepatides potential as a treatment for obesity-related HFpEF
Brand-name tirzepatide is manufactured under FDA-regulated Current Good Manufacturing Practices (cGMP) with extensive testing at every stage
These effects are compounded by the apoptosis of BBB microvascular endothelial cells caused by hyperglycemia and obesity
Note: At maximum doses (Trulicity 4.5mg), A1C reduction increases to 1.8%, making efficacy more comparable
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