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PMID 2766810

TH has a profound effect on carbohydrate metabolism

For less acute but worrying changes (like steadily rising blood pressure readings, persistent insomnia, or significant mood swings), contact your healthcare provider as soon as possible

In a substudy of people with fatty liver disease (MASLD): 12 mg dose: 86% reduction in liver fat at 48 weeks 8 mg dose: 81-82% reduction in liver fat This is huge for people with type 2 diabetes, because 5-7% of people with diabetes develop fatty liver disease and liver fibrosis

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These synergistic actions not only address the limitations of subcutaneous insulin regimens (e.g., hypoglycemia risk and poor patient compliance) but also provide a theranostic solution to reverse insulin resistance at its primary pathological site (Fig