At the pathological mechanism level, animal model experiments have verified direct nephrotoxic effects of metabolites, with relatively substantial evidence in this domain (102, 112)
(2) Pickart L, Vasquez-Soltero JM, Margolina A
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doi: 10.3390/biomedicines10102473 [DOI] [PMC free article] [PubMed] [Google Scholar] 109
Metabolic profiling reveals anomalous energy metabolism and oxidative stress pathways in chronic fatigue syndrome patients
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