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doi:10.3390/biom12010129 Pogribna M, Melnyk S, Pogribny I, Chango A, Yi P, James SJ

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GLP-1-based agents The focus of GLP-1RA development has predominantly been on designing GLP-1 derivatives resistant to DPP-4 enzymatic activity and exhibiting slow renal clearance through chemical modification and pharmaceutical formulation

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In another study , patients without T2D were more likely to stop using GLP-1 drugs: about 65% discontinued within a year, compared to 46% of those with type 2 diabetes