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Although, SMCs and ECs synthesize MCP-1, SMCs also moves to the tunica intima from the tunica media, where they differentiate into myofibroblasts and increase in the presence of PDGF [183, 184] and insulin via ROS-dependent phosphorylation of serine residues of IRS-1 [185, 186]

Wang Y, Guo S, Zhuang Y, Yun Y, Xu P, He X, Guo J, Yin W, Xu HE, Xie X, Jiang Y

Neurologia 23(9):55565 Zhu X, Liu J, Huang S et al (2019) Neuroprotective effects of isoliquiritigenin against cognitive impairment via suppression of synaptic dysfunction, neuronal injury, and neuroinflammation in rats with kainic acid-induced seizures [J]

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Tanguy S, Morel S, Berthonneche C, Toufektsian M-C, de Lorgeril M, Ducros V, et al

This route benefits individuals with chronic inflammation, weak digestion, or any condition affecting nutrient uptake