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Inefficiency of the phagocytosis process leads to the formation of residual lipid-protein granules that cannot be degraded, known as lipofuscin, and generation of ROS occurs from the constant exposure of lipofuscin to light and oxygen tension 1

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A.RabalO.Cuadrado-TejedorM.de MiguelI.Prez-GonzlezM.UgarteA.et al

21, 90113 10.1210/edrv.21.1.0390 [DOI] [PubMed] [Google Scholar] 30.Montero-Melendez T

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Activation of Glucagon-Like Peptide-1 Receptor Inhibits Tumourigenicity and Metastasis of Human Pancreatic Cancer Cells via PI3K/Akt Pathway