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Collection of blood and tissue samples At the end of the experimental period and following overnight fasting, rats were anesthetized using an intraperitoneal injection of ketamine (80 mg/kg body weight) and xylazine (10 mg/kg body weight)

Overall, these results suggest the high potential of NP4 as tumor-targeting anticancer agents

The NAD + -consuming enzymes produce NAM as a byproduct, of which high concentrations inhibit the activity of NAD + -consuming enzymes, providing feedback regulation

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